Egg freezing by vitrification

Egg freezing is a method of fertility preservation, which allows women to freeze eggs for later use. Women undergoing egg freezing generally take medication for a number of days to increase the growth of the eggs before they are collected in a short theatre procedure. If you are considering freezing your eggs it is important that you make an informed choice after discussing efficacy, safety and the costs.

Egg freezing at CREATE

CREATE Fertility’s Egg Vitrification (fast freezing) service allows you to preserve eggs for use in assisted IVF/ICSI conception treatments at a later date. Egg vitrification is a newly developed technique which allows eggs to be rapidly frozen, preserving their structural integrity. It was developed by Professor RC Chian, who set up our egg freezing facility and trained many of our embryologists in this new technique. The egg vitrification survival rate can be very high, over 80%, which helps to increase the success of having a baby from thawed frozen eggs in the future.

Why do women freeze their eggs?

There are many reasons why women choose to freeze their eggs. Some choose to freeze their eggs for social reasons, if they have not found the right partner for example, or if the time is not right to have a child. For others it may be a medical decision, in the face of a diagnosis such as cancer or being at risk of early menopause. Freezing eggs can be a very reassuring and empowering step, and it allows women to take control of their own fertility. As Medical Director Professor Geeta Nargund said ‘The development of egg Vitrification is a ground-breaking development in its ability to empower women and provide them with the freedom to choose when they have their children, and for these reasons I believe it to be a key milestone on the road to gender equality’.

Why CREATE?

CREATE offers a different approach to most other clinics, as we aim for 'quality over quantity' approach to obtaining eggs in mild stimulation cycles. This means we give lower doses of stimulation drugs in order to collect higher quality eggs for freezing, and work within the body’s natural cycle in order to collect the egg(s) naturally selected by the body. This approach means that treatment length is shorter and side effects are reduced. Treatment is therefore easier to fit around your day-to-day life.

To achieve the best results in terms of quality and quantity of eggs, it is usually recommended that you freeze eggs before you reach 35. The process takes around 2 weeks and involves taking the hormonal stimulation in order to mature an appropriate number of eggs in the ovaries, and requires 3-4 clinic visits for blood tests and medication. Once your egg sacks (follicles) have reached the appropriate size they will be emptied in the theatre in order to collect eggs. These will then be frozen using Vitrification technology, which is a fast-freezing process ensuring that the cells retain their structural integrity and are not damaged by the formation of ice crystals. By law, the eggs can be stored for a maximum of 10 years. In exceptional medical circumstances, this period can be reviewed in conjunction with our regulatory body, the HFEA.

Success

The success rates of egg freezing have increased, particularly following the development of Vitrification technology. Our Scientific Director, Prof RC Chian is a renowned pioneer and expert in this technology and has trained many of our embryologists in this new technique. The egg vitrification survival rate can be very high, over 80% of frozen eggs can now survive thawing. This high survival rate can help increase the success of having babies from thawed eggs in the future. 

Data published in scientific journals by the Instituto Valenciano de Infertilidad, Universidad de Valencia in Spain in 20102013 and 2014, show that of 3407 cycles of treatment for women freezing eggs for their own use, more than 80% of eggs were successfully thawed resulting in 1031 live births (i.e. 30% live birth rate), a similar rate to that we can expect when using fresh eggs. The success rate is even higher for younger women who freeze their eggs by vitrification. Women who freeze around 12 eggs before the age of 35 can have up to 50% live birth rate later. 

Please read our Medical Director's blogs for further information:

The truth behind the scaremongering headlines

12 FAQs about egg freezing 

Women can invest in their reproductive future with egg freezing 

Egg Freezing as part of gender equality

Dr Tugce Pehlivan
Laboratory Manager Wimbledon

Dr Tugce Pehlivan

Tugce graduated from Istanbul University Medical Faculty in 1997 after which she pursued a career in reproductive endocrinology, clinical embryology and pre- implantation genetic diagnosis (PGD....