What is PGS?

PGS is a technique used to assess embryos for chromosomal abnormalities. It involves the removal of one or more cells from embryos before they are transferred. This is followed by testing of the cells to find out the number of chromosomes, using a method called array-CGH. If the cells are found to have an abnormal chromosome number, then the embryo is less likely to implant. In this way embryos can be screened in order to select the most viable embryos for embryo transfer.  

PGS can be used by any person/couple undergoing an IVF cycle, but is most suitable for:

  • Patients of advanced maternal age
  • Patients with repeated miscarriage
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Advantages of PGS

Improves IVF success rates
Improves IVF success rates

Recent research has suggested that IVF success rates might be improved if embryos are screened for chromosome abnormalities with embryos that have the correct number of chromosomes given priority for transfer to the womb.

Accurate assessment of embryos
Accurate assessment of embryos

Data suggests that array-CGH results are correct over 95% of the time.

It can be used to diagnose Down Syndrome:
It can be used to diagnose Down Syndrome:

In PGS the number of chromosomes is examined and likely cases of Down Syndrome can be identified.

It can reduce misscarriage
It can reduce misscarriage

PGS is used to identify chromosomally normal embryos. These are more likely to be healthy, and are therefore more likely to implant successfully.

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From one of our expert advisors